Posts Tagged ‘Alzheimer’s Association’

The Use of Unproven Supplements

November 30, 2019

This post is based on an article titled “Study shows half of middle-aged Americans fear they’ll get dementia, use unproven supplements, in the Health & Science section of the 26 November 2019 issue of the Washington Post. The article begins, “About half of middle-aged Americans believe that they’re “very likely” to develop dementia a survey suggests, and many try to beat the odds with supplements such as ginkgo biloba and vitamins that aren’t proven to help.”

Data from the University of Michigan’s 2018 National Poll on Healthy Aging consists of a nationally representative survey of adults 50 to 80. 44.3% of the respondents said they were at lease somewhat likely to develop dementia, and 4.2% said they were very likely to develop dementia. Just 5.2% of the respondents said they had discussed dementia prevention with their doctors.

Regardless, 31.6% said they took fish oil or omega-3 fatty acids hoping that it would help lower the risk, and 39.2% took other vitamins or supplements. More than half of participants also believe doing crossword puzzles could help stave off dementia.

Study leader Donovan Maust of the University of Michigan wrote in the journal JAMA Neurology, “Given repeated failures of disease-preventing or disease modifying treatments for dementia, interest to treatment and prevention have shifted earlier in the disease process.”

These unproven supplements don’t work. Those who are solving crossword puzzles are on the right track, but more, prolonged cognitive effort is needed to stave off the disease. Similarly, certain computer games might be helpful, but playing them alone is insufficient.

The Alzheimer’s Association and drug developers are working on drugs to stop or eliminate the neurofibrally tangles and amyloid plaque, which are the defining characteristics of the disease. A former researcher into these drugs has argued that such drugs will never be discovered or developed. His arguments can be found in the healthy memory blog post titled The Myth of Alzheimer’s as well as in a book by the same title authored by Peter J. Whitehouse, M.D., Ph.D, and and Daniel George, M.Sc.

Moreover, many people have died and their autopsies have shown that their brains with these defining characteristics of the disease, but who never realized they had the disease, because they never had any of the cognitive or behavioral symptoms.

The reason offered for this result is that these individuals had built up a cognitive reserve. Cognitive activity had built up their brains so that, when they had these physical manifestations, their brains were able to work around them.

This is why the healthy memory blog strongly recommends growth mindsets where active reading and learning is maintained throughout one’s lifetime. This must also be supplemented by a healthy lifestyle. The practice of meditation and mindfulness can facilitate this healthy lifestyle.

© Douglas Griffith and healthymemory.wordpress.com, 2019. Unauthorized use and/or duplication of this material without express and written permission from this blog’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Douglas Griffith and healthymemory.wordpress.com with appropriate and specific direction to the original content.

A Healthier Heart and a Sharper Mind

July 29, 2018

The title of this post is identical to the title of an article by Tara Bahrampour in the 23 July 2018 issue of the Washington Post. The article begins, “Research presented Wednesday at the Alzheimer’s Association International Conference in Chicago found that at-risk people whose blood pressure was kept lower than the recommended level had a significant reduction in mild cognitive impair (MCI), the precursor to dementia/

The trial compared two strategies for maintaining blood pressure for people with an average age of around 68 with increased cardiovascular risk. One group received the standard care strategy at the time targeting systolic blood pressure (taken when the heart beats) to below 140 millimeters of mercury. The other group received the same medication, but in higher doses, with a target blood pressure of 120 mm or less.

Memory tests were also administered to assess participants for probable dementia and early memory loss. The group receiving the intensive approach had a 19% lower rate of new cases of MCI.

A subgroup was also assessed through magnetic resonance imaging (MRI), for white matter brain lesions that are associated with a higher risk of stroke, dementia and higher mortality. While both groups showed an increase in white matter lesions, the increase was significantly less in the intensive treatment group.

In the United States the rate of Alzheimer’s dementia is 10% for people 65 and older.

The researchers were excited with the results showing that the lowering of blood pressure with medication could also reduce the probability of dementia.

What the article does not mention is that blood pressure can be reduced without medication. Meditation can reduce blood pressure, heart rate and oxygen consumption. Research has also shown how meditation affected the body’s 40,000 genes and found that those who regularly meditated induced anti-oxidation and anti-inflammatory changes that counteracted the effects of stress on the body. There have been many healthymemory posts on meditation, the first being “The Relaxation Response.” The post provides instruction for getting the relaxation response, and benefits can be realized by doing this for 10 to 20 minutes once or twice a day.

Nor does the article mention that many have died with their brains full of the amyloid plaque and neurofibrillary tangles that are the defining characteristic of Alzheimer’s, but who never exhibited any behavioral or cognitive symptoms while they were living.

The reason offered for this fact is that these people had built up a cognitive reserve, presumably through certain types of cognitive activity. The healthy memory blog argues that growth mindsets, which by definition include Kahneman’s Type 2 processing, along with a healthy lifestyle and meditation, provide a means of building a cognitive reserve. These practices can lead to a more fulfilling life free of dementia. There are many, many healthymemoy blog posts on these topics.

© Douglas Griffith and healthymemory.wordpress.com, 2018. Unauthorized use and/or duplication of this material without express and written permission from this blog’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Douglas Griffith and healthymemory.wordpress.com with appropriate and specific direction to the original content.