Posts Tagged ‘Journal of Applied Physiology’

How Physical Exercise Contributes to a Healthy Memory

January 9, 2013

Enter “exercise” into the search block on the healthymemory blog and you will find a listing of many articles. Although the majority of them are discussing the benefits of cognitive exercise, you can still find many on the benefits of physical exercise. So a reasonable question is how can physical exercise benefit memory? Research indicating how this might happened in an article1 in Scientific American Mind,which, in turn, was reporting the results from a study in the Journal of Applied Physiology. This study, conducted by J. Mark Davis and his colleagues at the University of South Carolina, used mice. They found that quantities of a signaling molecule, which they called a “master regulator” of mitochondria production increased in the brain after a half hour a day of running on a treadmill. These brain cells of the mice also had more mitochondrial DNA as distinguished from the regular cellular DNA found in the nucleus. The researchers said that this provided “gold standard” evidence of more mitochondria. Mitochondria generate energy, and these increased mitochondria provide additional energy that allow the brain to work faster and more efficiently.

As we age, neurons naturally lose mitochondria. This loss of mitochondria can contribute to losses in brain and cognitive function resulting in dementia and other age-related declines in brain function. By increasing the energy supply new mitochondria can be produced offsetting this mitochondria loss.

Although we’ve known for a long time that physical exercise is good for both physical and cognitive health, we are beginning to gain insights as to why this is the case.

1Sutherland, S. (2012). How Exercise Jogs the Brain: Physical activity boosts cognition by improving neurons’ power supply. Scientific American Mind, March/April, 12.