Posts Tagged ‘Robert Knight’

The Loss of a Neuroscientist Who Should Have Been Awarded a Nobel Prize

September 6, 2017

And that neuroscientist is Marian Diamond who passed away on July 25, 2017 at the age of ninety. Her painstaking research showed that the body’s three-pound seat of consciousness was a dynamic structure of beautiful complexity, capable of development even in old age.

Prior to her research it was strongly believed the nervous system was fixed. We were stuck with the brain we were born with. And any damage to the brain was irreparable. The brain was a static and unchangeable entity that simply degenerated as we age.

Inspired by the research of psychologist Donald Hebb, she began studying the brains of lab rats. Rats that were raised alone, in small and desolate cages, had more trouble navigating a maze than did rats were raised in “enriched” cages, with toys and rat playmates. Through painstaking analyses of these rat brains she found that the cerebral cortices of rats in “enriched” cages were about 6% thicker than the rats in the “impoverished” cages.

Her findings, published in a 1964 paper with three colleagues, were a pivotal contribution to the long-running debate between nature and nurture, which seeks to determine the extent to which a person is shaped by their genes or by their life experiences.. UC-Berkely professor Robert Knight said “The idea that the brain could change based on environmental input and stimulation was felt to be silly, and that’s the boat she completely sank.

Further research generalized these conclusions to humans. Neuroplasticity was found to be ubiquitous. We continue to generate neurons until we die.

Dr. Diamond went on to develop a rich theory of brain plasticity summarized in the phrase use it or lose it. She outlined the following five factors crucial to brain development at any age: diet, exercise, challenge, newness, and love.

Later in her career she was given several sections of Albert Einstein’s brain. She found an unusually high amount of glial cells, which were thought to be a relatively unimportant part of the tissue that held the brain together. This discovery launched renewed interest in the role of glial cells, which are now believed to play a crucial role in cognitive processes.

This post is based in part on an obituary by Harrison Smith in the 31July 2017 Washington Post.

 

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